• Feedback
  • RSS Feed
  • Sitemap
Odisha News, Odisha Breaking News, Odisha Latest News || Ommcom News
  • Home
  • Odisha
  • Nation
  • World
  • Sports
  • Business
  • Entertainment
  • Videos
  • Science & Tech
  • Photo Gallery
  • ଓଡ଼ିଆରେ ପଢନ୍ତୁ
No Result
View All Result
  • Home
  • Odisha
  • Nation
  • World
  • Sports
  • Business
  • Entertainment
  • Videos
  • Science & Tech
  • Photo Gallery
  • ଓଡ଼ିଆରେ ପଢନ୍ତୁ
No Result
View All Result
Odisha News, Odisha Breaking News, Odisha Latest News || Ommcom News
Home Nation

IISER Bhopal Team Finds Circular RNA Molecule Behind HIV-1 Virus Replication

OMMCOM NEWS by OMMCOM NEWS
September 25, 2023
in Nation, Science & Tech

Bhopal:  Scientists from the Indian Institute of Science Education and Research (IISER) Bhopal has identified a specific circular RNA which plays a crucial role in multiplication of the AIDS-causing HIV-1 virus within the human body.

The study, published in the peer-reviewed journal Science Advances, revealed how the newly identified circular RNA molecule, called ciTRAN, influences the virus’s transcription process, which could potentially lead to novel therapeutic strategies against HIV-1.

The RNA or Ribonucleic acid is a molecule in living cells that carries genetic information and helps in the production of proteins. RNAs are in general straight-chain, free-end structures but one form of RNA called ‘circRNA’ forms a closed-loop.

The circRNA plays a pivotal role in regulating gene expression and is essential for various biological processes. Its role in HIV-1 replication has remained unclear for a long time.

“Characterising circular RNA can be tricky because it usually is less abundant, making it further challenging to detect in the native form. It is like trying to follow a complicated recipe,” said lead author Dr Ajit Chande, from Department of Biological Sciences, IISER Bhopal.

“Our results indicate that HIV-1 virus hijacks this host-encoded ciTRAN in such a way that it can use it to multiply efficiently. This discovery uncovers a previously unknown aspect of how viruses like HIV-1 overcome transmission barriers,” he added.

The team developed a novel approach called circDR-Seq to successfully capture circRNAs from T-cells (white blood cells) infected with the HIV-1 virus and identified a specific circRNA named ciTRAN.

Along with this, researchers also developed a molecule capable of inhibiting viral transcription that may be helpful in HIV-1 treatment.

By showing how ciTRAN promotes the virus’s ability to multiply efficiently, this study offers promising avenues for the development of novel therapeutic interventions. Moreover, the creation of a molecule capable of inhibiting viral transcription represents a significant leap in our understanding of combating HIV-1 and potentially other viruses.

(IANS)

ShareTweetSendSharePinShareSend
Previous Post

Bengal School Job Case: Calcutta HC Asks ED, CBI Officials To Explain Their Report

Next Post

Thundershower With Lightning Likely In 25 Odisha Dists Incl Bhubaneswar & Cuttack Within Next 3 Hrs

Related Posts

Nation

Tripura: Foundation Stone Laid For Integrated Aqua Park, To Scale Up Fish Production

May 18, 2025
Nation

Civil Servants Are The Backbone Of Governance: Tripura CM

May 18, 2025
Sleep apnea and depression – Is there a correlation?
Science & Tech

Wearable Sensor Can Monitor Obstructive Sleep Apnea Treatment Response: Study

May 18, 2025
Nation

Bengal: Three Illegal Bangladeshi Infiltrators Arrested In Nadia

May 18, 2025
Nation

Centre Opens Soil Library To Boost Maharashtra Farm Sector; Clean Plant Lab To Be Set Up In Pune Soon

May 18, 2025
Nation

Telangana CM Orders Probe Into Fire Accident

May 18, 2025
Next Post

Thundershower With Lightning Likely In 25 Odisha Dists Incl Bhubaneswar & Cuttack Within Next 3 Hrs

EET Hydrogen Commences FEED For Its HPP2 Plant

Mahatma Gandhi's Core Values Will Always Overpower Any Attack On Soul Of India, This Is Our Belief: Congress

Khimji
TPCODL
  • Feedback
  • RSS Feed
  • Sitemap

© 2025 - Ommcom News. All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In

Add New Playlist

No Result
View All Result
  • Home
  • Odisha
  • Nation
  • World
  • Sports
  • Business
  • Entertainment
  • Videos
  • Science & Tech
  • Photo Gallery
  • ଓଡ଼ିଆରେ ପଢନ୍ତୁ

© 2025 - Ommcom News. All Rights Reserved.